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N Acetylcysteine Nac, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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n acetylcysteine  (MedChemExpress)
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Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, <t>N-acetylcysteine;</t> NEC-1, necrostatin-1; Sch B, Schisandrin B.
N Acetylcysteine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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n acetyl l cysteine nac  (MedChemExpress)
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Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, <t>N-acetylcysteine;</t> NEC-1, necrostatin-1; Sch B, Schisandrin B.
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acetylcysteine  (MedChemExpress)
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Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, <t>N-acetylcysteine;</t> NEC-1, necrostatin-1; Sch B, Schisandrin B.
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n acetyl cysteine  (MedChemExpress)
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MedChemExpress n acetyl cysteine
Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, <t>N-acetylcysteine;</t> NEC-1, necrostatin-1; Sch B, Schisandrin B.
N Acetyl Cysteine, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, N-acetylcysteine; NEC-1, necrostatin-1; Sch B, Schisandrin B.

Journal: Oncology Reports

Article Title: Schisandrin B exhibits anti-proliferative effects by inducing ferroptosis in pancreatic cancer

doi: 10.3892/or.2026.9152

Figure Lengend Snippet: Cell death induced by Sch B is associated with ferroptosis. (A) Heat map and (B) volcano plot of the DEGs in PANC-1 cells between the Sch B group and the control group. KEGG annotation and enrichment analysis of the (C) upregulated and (D) downregulated DEGs in PANC-1 cells. Viability of (E) MIA PaCa-2 and (F) PANC-1 cells treated with Sch B (20 µM) with or without inhibitors, NEC-1 (50 µM), Z-VAD-FMK (50 µM), Fer-1 (10 µM), DFO (20 µM) and NAC (2 mM), was assessed using Cell Counting Kit-8 assay. **P<0.01. Con, control; DEG, differentially expressed gene; DFO, deferoxamine mesylate; Fer-1, ferrostatin-1; KEGG, Kyoto Encyclopedia of Genes and Genomes; NAC, N-acetylcysteine; NEC-1, necrostatin-1; Sch B, Schisandrin B.

Article Snippet: Ferrostatin-1 (Fer-1; cat. no. HY-100579), deferoxamine mesylate (DFO; cat. no. HY-B1625), Z-VAD-FMK (cat. no. HY-16658B), N-acetylcysteine (NAC; cat. no. HY-B0215) and necrostatin-1 (NEC-1; cat. no. HY-15760) were purchased from MedChemExpress.

Techniques: Control, Cell Counting